
THE HALLMARKS OF UNCONTROLLED gMG
~50% of patients (N=1140)
had moderate-to-severe gMG, defined as having a Myasthenia Gravis Activities of Daily Living (MG-ADL) score of 6 or above1*
26% of patients (N=372)
required IVIg within a 6-month period due to exacerbations or inability to reduce maintenance therapy8
~20% of patients (N=188)
will experience a potentially life-threatening myasthenic crisis requiring intubation at least once during their lifetime7,13
36% of patients (N=372)
report their treatments impact their ability to lead a normal life8
50-77% of patients (n=398)
50% of men and 77% of women reported intolerable side effects while taking prednisone10
UP TO
50% of patients (N=1077)
reported current disease symptoms associated with an unsatisfactory symptom state3,6,12
THE gMG DISEASE EXPERIENCE CAN
FEEL UNPREDICTABLE
For patients with chronically uncontrolled gMG, instability and
unpredictability are ever present.4,9

79-90% of patients never reach complete stable remission13,14‡
(n=677)

Fluctuations can be spontaneous, varying from day to day and from hour to hour9
INITIAL
~2-3 years
After being diagnosed, symptoms typically worsen,
reaching their peak within the first 2 years. But for 1 in 5 people, worsening symptoms may continue after 2 years.4
CONTINUAL
After the initial stage, people may continue to experience unpredictable and serious symptoms.1,7,15
EXACERBATIONS ARE UNPREDICTABLE
Although some triggers of intermittent worsening of symptoms have been identified, they
are not well understood, making the disease experience feel unpredictable for patients.4,9
IDENTIFIED TRIGGERS INCLUDE4,16:
- Mental and physical stress
- Seasonal changes
- Infections
- Certain medications
- Vaccinations
21-43%of patients
experienced ER visits and hospitalizations over the course of 6 months7‡ (n=76-741)
69% of patients
who experienced a myasthenic crisis have no identified precipitating factor11
(n=188)
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