UNDERSTANDING UNCONTROLLED gMG
As a chronic, autoimmune, neuromuscular disease, myasthenia gravis (MG) is a condition that may be present in your life for years.
Generalized myasthenia gravis (gMG) is a more severe form of MG, and may result in unpredictable symptoms that cause weakness throughout
your entire body.
What is uncontrolled gMG?
Watch the video to see what uncontrolled gMG means, and hear from others living with the condition.
Myth
gMG is well controlled for many people on treatment
Fact
For around half of the people living with gMG, their disease remains uncontrolled, meaning that they can experience debilitating chronic symptoms that impact daily life—even if they're on treatment
Myth
Exacerbations happen very rarely
Fact
Almost half of people experience an exacerbation (an acute worsening of symptoms) over a 6-month period
Myth
gMG is predictable and has only a minor impact on daily life
Fact
gMG can be unpredictable.
The symptoms can vary by the person, day, or hour—greatly impacting daily life
gMG CAN FEEL UNPREDICTABLE

Initial
~2-3 years
After being diagnosed, symptoms typically worsen, reaching their peak within the first 2 years. But for 1 in 5 people, worsening symptoms may continue after 2 years.
Continual
After the initial stage, people may continue to experience unpredictable and serious symptoms.

Initial
~2-3 years
After being diagnosed, symptoms typically worsen, reaching their peak within the first 2 years. But for 1 in 5 people, worsening symptoms may continue after 2 years.
Continual
After the initial stage, people may continue to experience unpredictable and serious symptoms.
Symptoms can feel unpredictable
If your gMG is uncontrolled, the unpredictability of this disease may always feel present.
gMG symptom fluctuations can be spontaneous, changing by the person, day, or hour.
2 out of 10 people with gMG may experience a myasthenic crisis that may require hospitalization at least once during their lifetime.
Triggers can feel unpredictable
gMG symptoms can worsen suddenly, caused by triggers beyond your control.
Triggers may include:
- Mental or physical stress
- Changes in weather
- Infections
- Certain drugs
- Vaccinations